Frailty index changes before and after stroke: Findings from four cohorts covering 18 countries
Frailty accelerates significantly both before and after an incident stroke, suggesting a bidirectional relationship between stroke and frailty. Integrating frailty assessment into stroke risk stratification, rehabilitation, and secondary prevention to optimize patient outcomes, particularly in aging populations.Data access statement:The datasets generated and analyzed during the current study are available on the HRS website (https://hrs.isr.umich.edu/), CHARLS (https://charls.pku.edu.cn/en), SHARE (https://share-eric.eu/), and ELSA (https://www.elsa-project).
Authors
- Xiaoyu Qian (ORCID: https://orcid.org/0000-0001-6954-1022)
- C. Wang (ORCID: https://orcid.org/0009-0005-0599-6999)
- Min Jin (ORCID: https://orcid.org/0000-0002-1390-4549)
- Cun-Xian Jia (ORCID: https://orcid.org/0000-0002-2651-147X)
- Feifei Jia (ORCID: https://orcid.org/0000-0002-5553-7433)
- Xueman Zhao
Institutions
- Shandong University (CN)
- Fourth People’s Hospital of Jinan (CN)
Publication Details
- Journal
- International Journal of Stroke
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1177/17474930251396655
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00