NSAID Use, Gastrointestinal Complications, and Burden of Disease in Osteoarthritis: Nordic Registry Study with Emphasis on Patients Below 60 Years

Across Nordic countries, patients with OA had more NSAID dispensations, and GI complications were more prevalent compared to matched individuals. Notably, this was already evident in younger patients under the age of 60, underscoring the need for comprehensive GI risk assessment for every patient with OA. The substantial burden of OA was also evidenced by considerable numbers of sick leave days and joint replacements.

Authors

Institutions

Publication Details

Journal
Rheumatology and Therapy
Published
2025-11-06
DOI
https://doi.org/10.1007/s40744-025-00803-4
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

NSAID Use, Gastrointestinal Complications, and Burden of Disease in Osteoarthritis: Nordic Registry Study with Emphasis on Patients Below 60 Years

Tore Kristian Kvien, Rita Freitas, Jan Jastorff, Elisabetta Mascia et al.
Rheumatology and Therapy
Inflammatory mediators and NSAID effects
article

NSAID Use, Gastrointestinal Complications, and Burden of Disease in Osteoarthritis: Nordic Registry Study with Emphasis on Patients Below 60 Years

Tore Kristian Kvien, Rita Freitas, Jan Jastorff, Elisabetta Mascia, Manfred Gross, Johan Liseth Hansen, Roman Böttger
article en

Abstract

Across Nordic countries, patients with OA had more NSAID dispensations, and GI complications were more prevalent compared to matched individuals. Notably, this was already evident in younger patients under the age of 60, underscoring the need for comprehensive GI risk assessment for every patient with OA. The substantial burden of OA was also evidenced by considerable numbers of sick leave days and joint replacements.

Rheumatology and TherapyVol. 13(1)
University of Oslo (NO), Starnberg Hospital (DE), Diakonhjemmet Hospital (NO), Grünenthal Group (Germany) (DE), Quantify Research (Sweden) (SE), AZ Sint-Lucas (BE), Grünenthal Group (Germany) (DE)
Openalex Percentile: Top 63%
Inflammatory mediators and NSAID effects
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

NSAID Use, Gastrointestinal Complications, and Burden of Disease in Osteoarthritis: Nordic Registry Study with Emphasis on Patients Below 60 Years — Tore Kristian Kvien, Rita Freitas, et al. · Rheumatology and Therapy (2025) | TGRS Research Map | TGRS