Elevated high‐density lipoprotein levels following acute graft‐versus‐host disease onset: a potential link to T‐cell dysfunction and increased relapse risk
AGvHD was linked to elevated HDL levels, potentially affecting T-cell-mediated graft-versus-leukaemia (GvL) activity and promoting relapse. HDL could therefore be a potential biomarker for the success of allo-SCT and a lever for improving patients' outcomes.
Authors
- Bénédikt Jacobs (ORCID: https://orcid.org/0009-0008-0173-9217)
- Dimitrios Mougiakakos (ORCID: https://orcid.org/0000-0002-2817-6660)
- Johannes Wittmann (ORCID: https://orcid.org/0000-0002-7275-9927)
- Heiko Bruns (ORCID: https://orcid.org/0000-0002-8463-6924)
- Romy Loschinski (ORCID: https://orcid.org/0000-0001-5067-7843)
- Diana Drettwan
- Franziska Karl (ORCID: https://orcid.org/0000-0003-0110-0743)
- Simon Völkl (ORCID: https://orcid.org/0000-0003-2193-3048)
- Andreas Mackensen
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Universitätsklinikum Erlangen (DE)
- Maschinenfabrik Reinhausen (Germany) (DE)
- Comprehensive Cancer Center Erlangen (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- Clinical & Translational Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/cti2.70060
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft