Case Report: Severe autoimmune hemolytic anemia in an elderly patient caused by warm-reactive IgG and IgA autoantibodies
The extended DAT testing is recommended for all patients with clinical and laboratory evidence of acute hemolysis. Early detection helps in avoiding further investigations and provide efficient management. Severe AIHA mediated by multiple autoantibodies requires early intensive combination therapy, including immunosuppressive agents, IVIG and plasma exchange.
Authors
- Ruiting Zhang (ORCID: https://orcid.org/0000-0002-8293-4979)
- Wenxia Xia
- Jihao Zhou (ORCID: https://orcid.org/0000-0002-2684-192X)
- Xiaoxuan Lai
- Junjie Hou (ORCID: https://orcid.org/0000-0002-8129-5618)
- Ke Peng (ORCID: https://orcid.org/0000-0003-0172-8725)
- Xinyou Zhang (ORCID: https://orcid.org/0000-0002-1942-997X)
- Jialing Lu (ORCID: https://orcid.org/0009-0001-8757-6154)
- Haiqing Lin
Institutions
- Southern University of Science and Technology (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Blood Center (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.3389/fimmu.2025.1664498
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sanming Project of Medicine in Shenzhen