Defined metabolic states shape T cell fate and function across culture conditions

This approach enables predictive, multiplexed metabolic profiling using minimal sample input and offers a scalable strategy to optimize T-cell manufacturing for memory enrichment and cytotoxic potency.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-11-06
DOI
https://doi.org/10.3389/fimmu.2025.1703095
Primary Topic
Viral Infectious Diseases and Gene Expression in Insects
Type
article
Field-Weighted Citation Impact
0.00
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article

Defined metabolic states shape T cell fate and function across culture conditions

Natasha Karassina, Kayla Sylvester, Jolanta Vidugirienė, Anthony Lauer et al.
Frontiers in Immunology
Viral Infectious Diseases and Gene Expression in Insects
article

Defined metabolic states shape T cell fate and function across culture conditions

Natasha Karassina, Kayla Sylvester, Jolanta Vidugirienė, Anthony Lauer, Gediminas Vidugiris
article en

Abstract

This approach enables predictive, multiplexed metabolic profiling using minimal sample input and offers a scalable strategy to optimize T-cell manufacturing for memory enrichment and cytotoxic potency.

Frontiers in ImmunologyVol. 16
Promega (United States) (US)
Openalex Percentile: Top 71%
Viral Infectious Diseases and Gene Expression in Insects
DOIOpen Access PDFOpenAlex
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Defined metabolic states shape T cell fate and function across culture conditions — Natasha Karassina, Kayla Sylvester, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS