Impact of COVID-19 therapeutics on the development of post-infectious lung fibrosis

PCPF remains a relevant sequela in COVID-19 survivors. Remdesivir and baricitinib use were associated with a reduced and increased risk of PCPF, respectively. Although adjusted for multiple confounders, residual indication bias of each treatment cannot be completely excluded. Therefore, prospective studies are needed to validate these associations.

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Publication Details

Journal
Frontiers in Microbiology
Published
2025-11-06
DOI
https://doi.org/10.3389/fmicb.2025.1677734
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of COVID-19 therapeutics on the development of post-infectious lung fibrosis

Chi Young Kim, Chul Hwan Park, Yong Jun Choi, Jae Hwa Cho et al.
Frontiers in Microbiology
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Impact of COVID-19 therapeutics on the development of post-infectious lung fibrosis

Chi Young Kim, Chul Hwan Park, Yong Jun Choi, Jae Hwa Cho, Ji Ye Jung, Min Kwang Byun, Hye Jung Park, Eun Hye Lee, Ji Eun Nam
article en

Abstract

PCPF remains a relevant sequela in COVID-19 survivors. Remdesivir and baricitinib use were associated with a reduced and increased risk of PCPF, respectively. Although adjusted for multiple confounders, residual indication bias of each treatment cannot be completely excluded. Therefore, prospective studies are needed to validate these associations.

Frontiers in MicrobiologyVol. 16
Yonsei University (KR), Severance Hospital (KR), Gangnam Severance Hospital (KR)
National Institutes of Health
Openalex Percentile: Top 53%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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