Establishment and characterization of preclinical models of human gynecologic tract carcinosarcomas demonstrates targetable FGFR1 alterations
These findings demonstrate the utility of patient-derived tumor models in the identification and the functional validation of potentially targetable molecular alterations in preclinical setting.
Authors
- Hannah Kim (ORCID: https://orcid.org/0000-0001-7138-6623)
- Marta Llauradó Fernández (ORCID: https://orcid.org/0000-0002-9589-2456)
- Mark Carey (ORCID: https://orcid.org/0000-0002-0473-6993)
- Yen‐Yi Lin (ORCID: https://orcid.org/0000-0002-4379-1231)
- Colin C. Collins (ORCID: https://orcid.org/0000-0001-6148-6110)
- Stanislav Volik (ORCID: https://orcid.org/0000-0001-8379-8887)
- Nelson K.Y. Wong (ORCID: https://orcid.org/0000-0002-7003-6020)
- Martin Köbel (ORCID: https://orcid.org/0000-0002-6615-2037)
- Pooja Praveen Kumar (ORCID: https://orcid.org/0000-0001-5143-6232)
- Yuzhuo Z. Wang (ORCID: https://orcid.org/0000-0002-9749-8591)
- DuPreez Smith
- Cheng‐Han Lee (ORCID: https://orcid.org/0000-0003-2094-1222)
- Yangxin Fu (ORCID: https://orcid.org/0000-0002-6573-0376)
- Hui Xue (ORCID: https://orcid.org/0000-0002-7578-0289)
- James A. Key
- Alice Y. Tong (ORCID: https://orcid.org/0009-0001-1721-3403)
- Stephane Le Bihan
Institutions
- BC Cancer Agency (CA)
- University of British Columbia (CA)
- University of Alberta (CA)
- University of Calgary (CA)
- Royal Alexandra Hospital (CA)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1016/j.tranon.2025.102591
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00