Immune checkpoint inhibitor-induced toxicity: a real-world analysis of the role of BMI

irAEs occurred more frequently in overweight/obese patients, mainly with metabolic abnormalities. These data underline the importance of a comprehensive clinical assessment, including weight and dysmetabolic comorbidities, of patients at baseline and during ICI therapy.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-11-06
DOI
https://doi.org/10.3389/fonc.2025.1659977
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Immune checkpoint inhibitor-induced toxicity: a real-world analysis of the role of BMI

Salvatore Cannavò, Angela Alibrandi, Massimiliano Berretta, Desirèe Speranza et al.
Frontiers in Oncology
Cancer Immunotherapy and Biomarkers
article

Immune checkpoint inhibitor-induced toxicity: a real-world analysis of the role of BMI

Salvatore Cannavò, Angela Alibrandi, Massimiliano Berretta, Desirèe Speranza, Martina Laganà, Rosaria Maddalena Ruggeri, Calogera Claudia Spagnolo, Mariacarmela Santarpia
article en

Abstract

irAEs occurred more frequently in overweight/obese patients, mainly with metabolic abnormalities. These data underline the importance of a comprehensive clinical assessment, including weight and dysmetabolic comorbidities, of patients at baseline and during ICI therapy.

Frontiers in OncologyVol. 15
University of Messina (IT), Azienda Ospedaliera Universitaria Policlinico "G. Martino" (IT)
Openalex Percentile: Top 55%
Cancer Immunotherapy and Biomarkers
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