Real‐World Effectiveness of Switching to Oral or Infusion Versus Injectable Disease‐Modifying Therapy in Pediatric Multiple Sclerosis
Switching from platform injectable to oral or infusion compared to other platform injectable DMT led to better disease control in pediatric MS. Long-term safety data are required. ANN NEUROL 2026;99:715-729.
Authors
- Aaron W. Abrams (ORCID: https://orcid.org/0000-0002-4607-5740)
- Alice Rutatangwa (ORCID: https://orcid.org/0000-0003-0843-7947)
- Mark Gorman (ORCID: https://orcid.org/0000-0003-3694-8832)
- Lauren Krupp (ORCID: https://orcid.org/0000-0001-7003-807X)
- Nikita Malani Shukla (ORCID: https://orcid.org/0000-0002-7322-676X)
- Leigh Charvet (ORCID: https://orcid.org/0000-0003-4429-9713)
- Emmanuelle L. Waubant (ORCID: https://orcid.org/0000-0001-5188-0157)
- Jayne Ness (ORCID: https://orcid.org/0000-0001-8017-0138)
- Yolanda Wheeler (ORCID: https://orcid.org/0000-0003-1391-4496)
- Lina Benson (ORCID: https://orcid.org/0000-0002-5393-0055)
- Moses Rodriguez (ORCID: https://orcid.org/0000-0001-6328-6497)
- Teri Schreiner (ORCID: https://orcid.org/0000-0002-3816-812X)
- Tanuja Chitnis (ORCID: https://orcid.org/0000-0002-9897-4422)
- Jennifer S. Graves (ORCID: https://orcid.org/0000-0003-1539-1940)
- Gregory Scott Aaen (ORCID: https://orcid.org/0000-0002-0408-2053)
- Soe Mar (ORCID: https://orcid.org/0000-0001-8449-2003)
- JOHN W. ROSE (ORCID: https://orcid.org/0000-0003-2382-5921)
- Mary R. Rensel (ORCID: https://orcid.org/0000-0001-9613-8394)
- Timothy E. Lotze (ORCID: https://orcid.org/0009-0003-2898-1963)
- Bianca Weinstock‐Guttman (ORCID: https://orcid.org/0000-0001-6732-151X)
- Kristen M. Krysko (ORCID: https://orcid.org/0000-0003-0090-597X)
- Theron Charles Casper (ORCID: https://orcid.org/0000-0001-7512-1294)
- Kimberly A. O’Neill (ORCID: https://orcid.org/0000-0001-6021-8683)
- Carla Francisco (ORCID: https://orcid.org/0000-0002-4628-3064)
- Jan‐Mendelt Tillema (ORCID: https://orcid.org/0000-0001-6933-8913)
- Michael Waltz (ORCID: https://orcid.org/0009-0008-8859-0362)
- Eva‐Chava M. Bernfeld
Institutions
- Boston Children's Hospital (US)
- St. Michael's Hospital (CA)
- Cleveland Clinic (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- University of Utah (US)
- Loma Linda University (US)
- University of Alabama at Birmingham (US)
- University of California San Diego (US)
- NYU Langone Health (US)
- Massachusetts General Hospital (US)
- Mayo Clinic in Arizona (US)
- Texas Children's Hospital (US)
- Boston Children's Museum (US)
- University of Colorado Anschutz Medical Campus (US)
- University at Buffalo, State University of New York (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1002/ana.78086
- Citations
- 1
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Biogen
- Multiple Sclerosis Society
- Genentech
- EMD Serono