Integrative analysis of genome and transcriptome reveals a novel regulator for pork intramuscular fat content

This study identifies MED17 as a novel regulator of IMF content in pigs, bridging genomic variation, gene expression networks, and phenotypic traits. These findings provide mechanistic insights into IMF deposition and highlight the potential of integrative multi-omics approaches for genetic improvement of pork quality traits in breeding programs.

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Publication Details

Journal
Genetics Selection Evolution
Published
2025-11-06
DOI
https://doi.org/10.1186/s12711-025-01014-9
Primary Topic
Genetic Mapping and Diversity in Plants and Animals
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrative analysis of genome and transcriptome reveals a novel regulator for pork intramuscular fat content

Xueyan Zhao, Jingxuan Li, Jiying Wang, Tizhong Shan et al.
Genetics Selection Evolution
Genetic Mapping and Diversity in Plants and Animals
article

Integrative analysis of genome and transcriptome reveals a novel regulator for pork intramuscular fat content

Xueyan Zhao, Jingxuan Li, Jiying Wang, Tizhong Shan, Yanping Wang, Yifan Ren, Wanli Jia
article en

Abstract

This study identifies MED17 as a novel regulator of IMF content in pigs, bridging genomic variation, gene expression networks, and phenotypic traits. These findings provide mechanistic insights into IMF deposition and highlight the potential of integrative multi-omics approaches for genetic improvement of pork quality traits in breeding programs.

Genetics Selection EvolutionVol. 57(1)
Poultry Research Institute (CN), Shandong Academy of Agricultural Sciences (CN), Livestock Breeding and Veterinary Department (MM), National Livestock Breeding Center (JP), Zhejiang University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Shandong Province
Openalex Percentile: Top 65%
Genetic Mapping and Diversity in Plants and Animals
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Integrative analysis of genome and transcriptome reveals a novel regulator for pork intramuscular fat content — Xueyan Zhao, Jingxuan Li, et al. · Genetics Selection Evolution (2025) | TGRS Research Map | TGRS