Long-term efficacy of anterior nucleus of the thalamus deep brain stimulation in drug-resistant epilepsy: a 5-year multicenter study
ANT-DBS significantly reduces SF in patients with DRE and shows stable long-term efficacy. The seizure onset zone, preoperative seizure severity and stimulation amplitude are critical predictors of postoperative outcomes, providing valuable information for optimal patient selection for this intervention.
Authors
- Xiaohui Du (ORCID: https://orcid.org/0000-0001-5553-4294)
- Yuanyuan Jiao (ORCID: https://orcid.org/0009-0000-7192-2676)
- Anchao Yang
- Qinglong Guo
- Tianqi Hu
- Jianguo Zhang (ORCID: https://orcid.org/0000-0001-7057-2862)
- Dongmei Gao (ORCID: https://orcid.org/0000-0003-3442-5704)
- Yuxin Wang (ORCID: https://orcid.org/0009-0003-1256-6140)
- Hutao Xie (ORCID: https://orcid.org/0000-0003-3725-5085)
- Kai Zhang (ORCID: https://orcid.org/0000-0003-4237-3115)
- Quan Zhang (ORCID: https://orcid.org/0000-0001-9715-4521)
- Shujuan Li (ORCID: https://orcid.org/0000-0003-4740-9615)
- Lin Sang
- Bowen Yang (ORCID: https://orcid.org/0000-0001-5218-7805)
- Fangang Meng (ORCID: https://orcid.org/0000-0002-8577-6443)
- Ming Shan (ORCID: https://orcid.org/0000-0002-4054-3718)
- Hua Zhang (ORCID: https://orcid.org/0009-0006-3833-3881)
Institutions
- Capital Medical University (CN)
- Anhui Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Beijing Shijitan Hospital (CN)
- Beijing Fengtai Hospital (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1186/s12916-025-04465-5
- Citations
- 6
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 8.34
Funders
- National Natural Science Foundation of China