Simplified rapid low-dose buprenorphine induction method for individuals using fentanyl: a case series

In this case series, the simplified rapid low-dose buprenorphine induction protocol was well-tolerated and 77.8% of patients using fentanyl were able to successfully initiate buprenorphine-naloxone maintenance. Benefits of this protocol are use of a single, standard dose of buprenorphine-naloxone, rapid induction timeline over only 8 h, and simple patient instructions.

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Publication Details

Journal
Addiction Science & Clinical Practice
Published
2025-11-06
DOI
https://doi.org/10.1186/s13722-025-00620-8
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Simplified rapid low-dose buprenorphine induction method for individuals using fentanyl: a case series

Ryan Alexander, Noah Woford
Addiction Science & Clinical Practice
Opioid Use Disorder Treatment
article

Simplified rapid low-dose buprenorphine induction method for individuals using fentanyl: a case series

Ryan Alexander, Noah Woford
article en

Abstract

In this case series, the simplified rapid low-dose buprenorphine induction protocol was well-tolerated and 77.8% of patients using fentanyl were able to successfully initiate buprenorphine-naloxone maintenance. Benefits of this protocol are use of a single, standard dose of buprenorphine-naloxone, rapid induction timeline over only 8 h, and simple patient instructions.

Addiction Science & Clinical PracticeVol. 20(1)
Lincoln Memorial University (US), Webb School of Knoxville (US), University of Tennessee at Knoxville (US)
Openalex Percentile: Top 57%
Opioid Use Disorder Treatment
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