Genetic Diversity and Temporal Shifts of Porcine Reproductive and Respiratory Syndrome Virus Type 2 (PRRSV-2) Strains in Japan (2020–2023): Evidence of Modified Live Vaccine Influence on Cluster Distribution
These findings demonstrated the temporal changes in the genetic diversity of Cluster III and provided suggestions of a possible influence that MLV usage influences PRRSV-2 cluster distribution, with Clusters I and II likely representing vaccine-origin viruses. The marked heterogeneity of Cluster IV also highlights the limitations of the current cluster-based classification.
Authors
- Kohei Makita (ORCID: https://orcid.org/0000-0002-0181-0246)
- Osamu Taira (ORCID: https://orcid.org/0009-0009-2328-6682)
- Nobuyuki Tsutsumi (ORCID: https://orcid.org/0009-0008-7880-6748)
- Ryota Matsuyama (ORCID: https://orcid.org/0000-0002-7296-0129)
- Ryosuke Takai
- Atsushi Kato (ORCID: https://orcid.org/0009-0004-0064-521X)
- Yuko Yonezawa
- Ryohei Nukui
Institutions
- Nippon Institute for Biological Science (JP)
- Eiken Chemical (Japan) (JP)
- National Institute of Animal Health (JP)
- Rakuno Gakuen University (JP)
Publication Details
- Journal
- Epidemiologia
- Published
- 2025-11-06
- DOI
- https://doi.org/10.3390/epidemiologia6040077
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00