Atypical ulcerative cutaneous tuberculosis revealing disseminated mycobacterial infection: case report with diagnostic and therapeutic challenges
This case highlights the diagnostic challenge and chronicity of CTB, particularly in the ulcerative presentation. The patient developed disseminated tuberculosis with cutaneous involvement without any recent travel or known tuberculosis exposure, and the probable etiology is latent reactivation. There should be a high index of suspicion for CTB in patients presenting with indolent, atypical skin lesions, particularly those from an endemic region. Early diagnosis and prolonged therapy are crucial to avoid long-term sequelae.
Authors
- Franca Del Nonno (ORCID: https://orcid.org/0000-0001-6664-9257)
- Daniele Colombo (ORCID: https://orcid.org/0000-0001-8607-2950)
- Francesca Faraglia
- Emanuele Nicastri (ORCID: https://orcid.org/0000-0002-5606-8712)
- Serena Vita (ORCID: https://orcid.org/0000-0002-2573-732X)
- Alessandra D’Abramo (ORCID: https://orcid.org/0000-0002-5160-9743)
- Antonia Maria Olivieri
- Alessandra Scarabello (ORCID: https://orcid.org/0000-0003-0589-3904)
- Enrico Mirante
- Alberta Villanacci (ORCID: https://orcid.org/0009-0005-6011-4709)
- Gina Gualano
- Andrea Mariano
- Claudia Palazzolo (ORCID: https://orcid.org/0000-0002-6999-5515)
- Stefania Ianniello
Institutions
- Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani (IT)
- St. Eugenio Hospital (IT)
Publication Details
- Journal
- Infectious Diseases of Poverty
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1186/s40249-025-01377-7
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute