Not All Bone Lesions After Breast Cancer Treatment Indicate Metastasis: A Case Report and Review of the Literature

Breast cancer is one of the osteophilic cancers. However, the appearance of bone-related symptoms in a pretreated patient is not always indicative of bone metastases. We report a case of a patient pretreated for localized breast cancer who subsequently developed bone symptoms, with lytic bone lesions on spinal MRI, which were ultimately found to be related to multiple myeloma. This clinical case outlines the diagnostic difficulties of multiple myeloma in patients with a history of breast cancer, highlighting the risk of delayed multiple myeloma management.

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Publication Details

Journal
Cureus
Published
2025-11-06
DOI
https://doi.org/10.7759/cureus.96191
Primary Topic
Management of metastatic bone disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Not All Bone Lesions After Breast Cancer Treatment Indicate Metastasis: A Case Report and Review of the Literature

Mohamed Kaakoua, Aznag Mohamed Amine, Hicham Yahyaoui, Soukayna Boujmadi et al.
Cureus
Management of metastatic bone disease
article

Not All Bone Lesions After Breast Cancer Treatment Indicate Metastasis: A Case Report and Review of the Literature

Mohamed Kaakoua, Aznag Mohamed Amine, Hicham Yahyaoui, Soukayna Boujmadi, Ismail Essadi, Hamza Laabbar, Nada Ebbadi, Moussa Abdolaziz Sawadogo
article en

Abstract

Breast cancer is one of the osteophilic cancers. However, the appearance of bone-related symptoms in a pretreated patient is not always indicative of bone metastases. We report a case of a patient pretreated for localized breast cancer who subsequently developed bone symptoms, with lytic bone lesions on spinal MRI, which were ultimately found to be related to multiple myeloma. This clinical case outlines the diagnostic difficulties of multiple myeloma in patients with a history of breast cancer, highlighting the risk of delayed multiple myeloma management.

CureusVol. 17(11)
Military Hospital (PK), Hôpital Militaire Avicenne (MA)
Openalex Percentile: Top 49%
Management of metastatic bone disease
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