Malformations of cortical development on fetal MRI

Neuronal migrational anomalies, cortical dysplasias, hemimegalencephaly, and microcephalies are collectively termed malformations of cortical development (MCD). MCDs have multifactorial etiologies including genetic, environmental, vascular, and infectious insults between the late 1<sup>st</sup> trimester and late 2<sup>nd</sup> trimester. Neonatal correlates of various neuronal migration anomalies detected on fetal magnetic resonance imaging are illustrated. Physiologic immaturity of sulci and certain mimics of migration anomalies can pose a challenge, and these are also outlined.

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Publication Details

Journal
Journal of Clinical Imaging Science
Published
2025-11-06
DOI
https://doi.org/10.25259/jcis_123_2023
Primary Topic
Fetal and Pediatric Neurological Disorders
Type
article
Field-Weighted Citation Impact
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article

Malformations of cortical development on fetal MRI

Gayathri Sreedher, Emily Janitz, Shankar Srinivas Ganapathy, Kyle Hunter
Journal of Clinical Imaging Science
Fetal and Pediatric Neurological Disorders
article

Malformations of cortical development on fetal MRI

Gayathri Sreedher, Emily Janitz, Shankar Srinivas Ganapathy, Kyle Hunter
article en

Abstract

Neuronal migrational anomalies, cortical dysplasias, hemimegalencephaly, and microcephalies are collectively termed malformations of cortical development (MCD). MCDs have multifactorial etiologies including genetic, environmental, vascular, and infectious insults between the late 1<sup>st</sup> trimester and late 2<sup>nd</sup> trimester. Neonatal correlates of various neuronal migration anomalies detected on fetal magnetic resonance imaging are illustrated. Physiologic immaturity of sulci and certain mimics of migration anomalies can pose a challenge, and these are also outlined.

Journal of Clinical Imaging ScienceVol. 15
MetroHealth (US), Akron Children's Hospital (US)
Openalex Percentile: Top 55%
Fetal and Pediatric Neurological Disorders
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