Prognostic implications of microRNA-107 in esophageal cancer: a retrospective cohort study
miR-107 downregulation is a robust predictor of aggressive ESCC phenotypes and poor survival. It holds promise as a clinical biomarker for risk stratification and personalized therapy. Future studies should validate these findings in multicenter cohorts and elucidate miR-107's functional mechanisms.
Authors
- Jinhua Ye (ORCID: https://orcid.org/0000-0002-8105-8903)
- Caifeng Jiang
- Jie Sun (ORCID: https://orcid.org/0000-0002-3466-1371)
- Jin Zhang (ORCID: https://orcid.org/0000-0001-7145-7823)
- Yuqi Chen (ORCID: https://orcid.org/0000-0002-2928-556X)
Institutions
- Nanjing General Hospital of Nanjing Military Command (CN)
- Soochow University (CN)
- Suzhou Municipal Hospital (CN)
- Second Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-11-06
- DOI
- https://doi.org/10.7717/peerj.20327
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nanjing General Hospital of Nanjing Military Command