Sex differences in the prognostic value of urinary albumin-to-creatinine ratio for coronary artery disease and cardiovascular events in people with type 2 diabetes and normoalbuminuria
Within the normoalbuminuric range, UACR is associated with greater CAD burden and higher 6-year MACE risk, with sex-specific differences. These findings suggest potential sex-related variation in the prognostic value of high-normal albuminuria, particularly among women, warranting validation in larger and more diverse cohorts.
Authors
- Carolina Hernández-Carballo (ORCID: https://orcid.org/0009-0001-9177-8103)
- Alberto Martín-Olivera (ORCID: https://orcid.org/0009-0009-9805-0965)
- Juan F. Navarro‐González (ORCID: https://orcid.org/0000-0002-5015-7474)
- Ainhoa González-Luis
- Javier Donate‐Correa (ORCID: https://orcid.org/0000-0001-7389-7347)
- Carmen Mora‐Fernández (ORCID: https://orcid.org/0000-0003-1570-6332)
- Orlando Siverio-Morales
Institutions
- Universidad de La Laguna (ES)
- Instituto de Salud Carlos III (ES)
- Hospital Universitario Nuestra Señora de Candelaria (ES)
- Universidad Fernando Pessoa Canarias (ES)
- Gobierno de Canarias (ES)
- Sociedad Española de Nefrología (ES)
- Gobierno de Aragón (ES)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1186/s12933-025-02996-y
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto de Salud Carlos III
- European Regional Development Fund