Association Between Unremitting PTSD and Smaller Right Hippocampal Volume Among Veterans 30 Years After Combat

These results support an emerging literature suggesting that reduced hippocampal volume observed among individuals with PTSD may be related to failure to recover from rather than to the development of PTSD after trauma exposure. These findings may define a subpopulation of combat veterans who are at increased risk for long-term failure to recover from PTSD because of their smaller right hippocampi.

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Publication Details

Journal
Journal of Neuropsychiatry
Published
2025-11-06
DOI
https://doi.org/10.1176/appi.neuropsych.20250059
Primary Topic
Posttraumatic Stress Disorder Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between Unremitting PTSD and Smaller Right Hippocampal Volume Among Veterans 30 Years After Combat

Natasha B. Lasko, Roger K. Pitman, Mark W. Gilbertson, Kaloyan S. Tanev et al.
Journal of Neuropsychiatry
Posttraumatic Stress Disorder Research
article

Association Between Unremitting PTSD and Smaller Right Hippocampal Volume Among Veterans 30 Years After Combat

Natasha B. Lasko, Roger K. Pitman, Mark W. Gilbertson, Kaloyan S. Tanev, Martha E. Shenton, Scott P. Orr
article en

Abstract

These results support an emerging literature suggesting that reduced hippocampal volume observed among individuals with PTSD may be related to failure to recover from rather than to the development of PTSD after trauma exposure. These findings may define a subpopulation of combat veterans who are at increased risk for long-term failure to recover from PTSD because of their smaller right hippocampi.

Journal of Neuropsychiatry
Massachusetts General Hospital (US)
Openalex Percentile: Top 55%
Posttraumatic Stress Disorder Research
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