Simultaneous co-delivery of a reporter EGFP gene and doxorubicin to HepG2 cells using AuNPs-Functionalized Graphene Oxide Nanostructures

The GO-Au nanostructure effectively co-delivered DOX and EGFP into HCC cells, exhibiting improved transfection efficiency, along with reduced toxicity to normal cells. This dual-functional nanoplatform presents a promising approach for real-time monitoring of gene and drug delivery.

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Publication Details

Journal
Nanomedicine
Published
2025-11-06
DOI
https://doi.org/10.1080/17435889.2025.2582462
Primary Topic
Graphene and Nanomaterials Applications
Type
article
Field-Weighted Citation Impact
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article

Simultaneous co-delivery of a reporter EGFP gene and doxorubicin to HepG2 cells using AuNPs-Functionalized Graphene Oxide Nanostructures

Fatemeh Oroojalian, Ali Khorsand Zak, S. Akbar Hosseini, Abbas Nikravesh
Nanomedicine
Graphene and Nanomaterials Applications
article

Simultaneous co-delivery of a reporter EGFP gene and doxorubicin to HepG2 cells using AuNPs-Functionalized Graphene Oxide Nanostructures

Fatemeh Oroojalian, Ali Khorsand Zak, S. Akbar Hosseini, Abbas Nikravesh
article en

Abstract

The GO-Au nanostructure effectively co-delivered DOX and EGFP into HCC cells, exhibiting improved transfection efficiency, along with reduced toxicity to normal cells. This dual-functional nanoplatform presents a promising approach for real-time monitoring of gene and drug delivery.

NanomedicineVol. 21(1)
North Khorasan University of Medical Sciences (IR), Esfarayen University of Technology (IR)
Openalex Percentile: Top 68%
Graphene and Nanomaterials Applications
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Simultaneous co-delivery of a reporter EGFP gene and doxorubicin to HepG2 cells using AuNPs-Functionalized Graphene Oxide Nanostructures — Fatemeh Oroojalian, Ali Khorsand Zak, et al. · Nanomedicine (2025) | TGRS Research Map | TGRS