Fibrosis in Asymptomatic Steatotic Liver Disease With Normal Alanine Aminotransferase: Analysis of 2448 Health Check‐Up Cohort by Ultrasound Attenuation Imaging and Shear Wave Elastography
A considerable proportion of patients with SLD and with normal ALT levels have unrecognized significant fibrosis. These findings highlight the diagnostic limitations of ALT and conventional indices and the urgent need for alternative strategies incorporating noninvasive imaging and direct fibrosis biomarkers.
Authors
- Yuji Kita
- Yuji Shimada
- Shunsuke Sato (ORCID: https://orcid.org/0000-0002-7480-7283)
- Hidehiko Kawai (ORCID: https://orcid.org/0000-0003-2213-7166)
- Takuya Genda (ORCID: https://orcid.org/0000-0003-0006-8948)
- Masahiro Yamaguchi (ORCID: https://orcid.org/0000-0001-5094-506X)
- Ayato Murata
- Hiroki Nago
- Rihwa Om
- Sho Sato
- Yuji Ikeda (ORCID: https://orcid.org/0000-0002-0036-2365)
- Yoko Kato (ORCID: https://orcid.org/0000-0002-4328-1987)
- Yuichiro Terai
Institutions
- Juntendo University Shizuoka Hospital (JP)
- Shizuoka Medical Center (JP)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1111/jgh.70136
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00