Ginsenoside Rb1 restores dental pulp by promoting odontogenic differentiation of dental pulp stem cells via the TGF-β/Smad signaling pathway

G-Rb1 promotes odontoblastic differentiation in hDPSCs and enhances reparative dentin formation via the TGF-β/Smad signaling pathway. These findings highlight the potential of G-Rb1 as a therapeutic agent for dental pulp repair and regeneration.

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Publication Details

Journal
Journal of Ginseng Research
Published
2025-11-06
DOI
https://doi.org/10.1016/j.jgr.2025.11.001
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
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article

Ginsenoside Rb1 restores dental pulp by promoting odontogenic differentiation of dental pulp stem cells via the TGF-β/Smad signaling pathway

Myeongkwan Jih, Jaeyoung Ryu, Hyekyoung You, Ok Hyung Nam et al.
Journal of Ginseng Research
Endodontics and Root Canal Treatments
article

Ginsenoside Rb1 restores dental pulp by promoting odontogenic differentiation of dental pulp stem cells via the TGF-β/Smad signaling pathway

Myeongkwan Jih, Jaeyoung Ryu, Hyekyoung You, Ok Hyung Nam, Seong Eun Kim, Young Kim, Si Won Kang
article en

Abstract

G-Rb1 promotes odontoblastic differentiation in hDPSCs and enhances reparative dentin formation via the TGF-β/Smad signaling pathway. These findings highlight the potential of G-Rb1 as a therapeutic agent for dental pulp repair and regeneration.

Journal of Ginseng ResearchVol. 50(1)
Chonnam National University (KR), Chosun University (KR), Kyung Hee University (KR), Kyung Hee University Medical Center (KR)
Openalex Percentile: Top 53%
Endodontics and Root Canal Treatments
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