NeuroSpikeX: Comprehensive detection and characterization of neuronal calcium dynamics

NeuroSpikeX is a user-friendly tool for the quantitative analysis of neuronal calcium dynamics. It provides robust calcium spike detection, comprehensive network metrics, and intuitive graphical interfaces. NeuroSpikeX seamlessly integrates into existing workflows using outputs from the established algorithm NeuroCa, enhancing accuracy and reproducibility. The code effectively analyzes calcium dynamics across numerous in vitro datasets containing multiple experimental time points. NeuroSpikeX facilitates detailed cell and network analyses in large datasets, making rigorous calcium transient characterization accessible to researchers with minimal coding expertise.