Trends in uncomplicated and severe malaria following seasonal malaria chemoprevention administration in Nouna, Burkina Faso: a quasi-experimental pre-post study
In programme settings, at the population level, SMC administration was associated with a substantial reduction in uncomplicated and severe malaria, though this effect was limited to the immediate weeks following administration. The gradual increase in malaria rates by the third week suggests a shorter duration of protection than previously observed. Extending the areas where 5 rounds of distribution occur may be necessary to effectively prevent malaria infections in regions with a longer transmission season. Regular evaluation of local malaria trends and impact of SMC can help further tailor and optimize SMC programmes for specific regional contexts.
Authors
- Catherine E. Oldenburg (ORCID: https://orcid.org/0000-0002-0763-399X)
- Benjamin F. Arnold (ORCID: https://orcid.org/0000-0001-6105-7295)
- David V. Glidden (ORCID: https://orcid.org/0000-0001-5888-1419)
- Ali Sié (ORCID: https://orcid.org/0000-0002-3959-2520)
- Valentin Boudo (ORCID: https://orcid.org/0000-0001-6194-6164)
- Elodie Lebas (ORCID: https://orcid.org/0000-0001-5741-7155)
- Mamadou Ouattara (ORCID: https://orcid.org/0000-0002-0011-6789)
- Elisabeth Gebreegziabher (ORCID: https://orcid.org/0000-0003-2454-5016)
- Mamadou Bountogo (ORCID: https://orcid.org/0000-0001-5010-1617)
- Thomas M. Lietman (ORCID: https://orcid.org/0000-0001-8216-0240)
- Huiyu Hu (ORCID: https://orcid.org/0000-0003-2866-9358)
- Thierry Ouédraogo
- Boubacar Coulibaly (ORCID: https://orcid.org/0000-0002-4777-6741)
Institutions
- Carl von Ossietzky Universität Oldenburg (DE)
- University of California, San Francisco (US)
- San Francisco Foundation (US)
- University of California System (US)
- Centre de Recherche en Santé de Nouna (BF)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1186/s12936-025-05597-y
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation