Correlation between different levels of Her-2 protein expression and the efficacy of neoadjuvant therapy in Her-2 positive breast cancer

Her-2 (3+) expression correlates with superior pCR rates, underscoring the need for further research to refine patient selection for optimized targeted therapy benefits.

Authors

Zhe Cui (ORCID: https://orcid.org/0000-0002-3345-5197)
Wenhui Wang (ORCID: https://orcid.org/0000-0001-7198-4017)
Hongbo Li (ORCID: https://orcid.org/0000-0002-9024-1574)
Zhiyong Wang (ORCID: https://orcid.org/0000-0002-8043-0312)
Yandong Li (ORCID: https://orcid.org/0000-0001-8153-081X)

Institutions

Beihua University (CN)
Jinhua Academy of Agricultural Sciences (CN)
Jinhua Central Hospital (CN)

Publication Details

Journal: Frontiers in Oncology
Published: 2025-11-06
DOI: https://doi.org/10.3389/fonc.2025.1673234
Primary Topic: HER2/EGFR in Cancer Research
Type: article
Field-Weighted Citation Impact: 0.00

Funders

People's Government of Jilin Province

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article

Correlation between different levels of Her-2 protein expression and the efficacy of neoadjuvant therapy in Her-2 positive breast cancer

Zhe Cui, Wenhui Wang, Hongbo Li, Zhiyong Wang et al.

Nov 6, 2025

Frontiers in Oncology

HER2/EGFR in Cancer Research

article

Correlation between different levels of Her-2 protein expression and the efficacy of neoadjuvant therapy in Her-2 positive breast cancer

Zhe Cui, Wenhui Wang, Hongbo Li, Zhiyong Wang, Yandong Li

November 6, 2025article en

Abstract

Her-2 (3+) expression correlates with superior pCR rates, underscoring the need for further research to refine patient selection for optimized targeted therapy benefits.

Frontiers in OncologyVol. 15

Beihua University (CN), Jinhua Academy of Agricultural Sciences (CN), Jinhua Central Hospital (CN)

People's Government of Jilin Province

Openalex Percentile: Top 55%

HER2/EGFR in Cancer Research

DOI Open Access PDF OpenAlex

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Correlation between different levels of Her-2 protein expression and the efficacy of neoadjuvant therapy in Her-2 positive breast cancer — Zhe Cui, Wenhui Wang, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS