The Relationship Between Restless Leg Syndrome, Sleep Quality and Quality of Life Among Patients Undergoing Hemodialysis

Introduction: Hemodialysis (HD) burdens patients with poor sleep quality and quality of life, with restless leg syndrome (RLS) affecting 15-20% of end-stage renal failure patients. Understanding RLS's connection can help healthcare professionals improve patients' self-care practices. This study aimed to explore the relationship between restless leg syndrome, sleep quality and quality of life among patients undergoing hemodialysis in Indonesia. Materials and methods: A cross-sectional research design was employed to recruit patients who receive HD three times a week for at least six months at two hemodialysis centers in Indonesia. International RLS Study Group Scale (IRLSSG), Pittsburgh Sleep Quality Index (PSQI), and the Kidney Disease Quality of Life Short Form (KDQOL-SFTM v1.3) was used to measure study variables. The linear regression method was used to evaluate the parameters that significantly correlated with the QOL. Results: Of 194 participants were recruited in this study. the mean age was 55.50 ± 10.72, 55.7% male, 51.6% had education level above senior high school, 90.7% married, and 69.1% unemployed. length of haemodialysis (B=2.047, SE=0.614) were significant positively associated with quality of life in HD patient (p<0.05). In addition, number of comorbidities (B=3.915, SE=00.142) and sleep quality (-3.928, SE=0.831) were significant positively associated with QOL (p<0.05). While, RLS (B=-4.872, SE=0.126) was significant negatively associated with QOL (p<0.05). Conclusion: The study revealed a negative correlation between higher scores on RLS and poor sleep quality, and the overall quality of life. Measures should be performed to treat RLS symptoms, enhance sleep quality, and increase QOL in HD patients.