Engineered virus-hunter vaccine overcomes HBV immune tolerance
This innovative HBV vaccine strategy actively captures viruses, overcoming the tolerogenic immune microenvironment of chronic HBV infection, offering a novel strategy for the treatment of chronic HBV infection and other immune-tolerant diseases.
Authors
- Tianying Zhang (ORCID: https://orcid.org/0000-0002-2477-329X)
- Jian-cheng Ding (ORCID: https://orcid.org/0000-0002-6845-7643)
- Fentian Chen
- Hongye Zeng (ORCID: https://orcid.org/0000-0001-8962-559X)
- Shiting Yang
- Wenjing Ning
- Yichao Jiang (ORCID: https://orcid.org/0009-0001-8657-2776)
- Xiaojing Qin (ORCID: https://orcid.org/0000-0001-9848-2228)
- Xu Lin (ORCID: https://orcid.org/0000-0002-5346-4605)
- Ningshao Xia (ORCID: https://orcid.org/0000-0003-0179-5266)
- Yueting Xiong (ORCID: https://orcid.org/0009-0008-8471-9800)
- Quan Yuan (ORCID: https://orcid.org/0000-0001-5487-561X)
- Chao Liu (ORCID: https://orcid.org/0000-0003-2814-3794)
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Tao Xu (ORCID: https://orcid.org/0000-0002-6897-5993)
- Peng Wang
- Liang Zhang (ORCID: https://orcid.org/0000-0002-2512-2384)
- Wenxin Luo (ORCID: https://orcid.org/0000-0002-0557-3196)
- Yalin Wang (ORCID: https://orcid.org/0000-0002-6241-735X)
- Xue Liu (ORCID: https://orcid.org/0000-0003-4779-8948)
- Yuanzhi Chen (ORCID: https://orcid.org/0000-0003-3627-5551)
- Han Liu (ORCID: https://orcid.org/0000-0003-4476-2253)
Institutions
- Xiamen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Gut
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1136/gutjnl-2025-335806
- Citations
- 1
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35