Assessing anti-plaque efficiency of a herbal dentifrice

Dental plaque is a key factor in gingivitis and periodontitis, requiring effective control measures. This randomized, double-blind clinical trial compared an herbal dentifrice (neem, clove and tea tree oil), a conventional fluoride dentifrice and a placebo in 90 participants with mild gingivitis. Plaque Index (PI) and Gingival Index (GI) were recorded at baseline, 2 weeks and 4 weeks. At 4 weeks, the herbal dentifrice showed the greatest reductions in PI (60.7%) and GI (55.7%) compared to fluoride (48.6%, 41.8%) and placebo (21.4%, 13.2%), with significant intergroup differences (p < 0.001). The herbal dentifrice demonstrated superior anti-plaque and anti-gingivitis efficacy, supporting its role as a natural oral hygiene alternative.

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Bioinformation
Published
2025-10-31
DOI
https://doi.org/10.6026/973206300213828
Primary Topic
Oral microbiology and periodontitis research
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article
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article

Assessing anti-plaque efficiency of a herbal dentifrice

Sonia Sharma, Debadrita Ghosh, Shalini Singh, Vishal Yadav et al.
Bioinformation
Oral microbiology and periodontitis research
article

Assessing anti-plaque efficiency of a herbal dentifrice

Sonia Sharma, Debadrita Ghosh, Shalini Singh, Vishal Yadav, A. Nagaraja, Nandini Komaravelli
article en

Abstract

Dental plaque is a key factor in gingivitis and periodontitis, requiring effective control measures. This randomized, double-blind clinical trial compared an herbal dentifrice (neem, clove and tea tree oil), a conventional fluoride dentifrice and a placebo in 90 participants with mild gingivitis. Plaque Index (PI) and Gingival Index (GI) were recorded at baseline, 2 weeks and 4 weeks. At 4 weeks, the herbal dentifrice showed the greatest reductions in PI (60.7%) and GI (55.7%) compared to fluoride (48.6%, 41.8%) and placebo (21.4%, 13.2%), with significant intergroup differences (p < 0.001). The herbal dentifrice demonstrated superior anti-plaque and anti-gingivitis efficacy, supporting its role as a natural oral hygiene alternative.

BioinformationVol. 21(10)
Government Medical College (IN), Safdarjang Hospital (IN), KPC Medical College and Hospital (IN), Maharaja Engineering College (IN), SVS Medical College (IN), Seema Dental College and Hospital (IN), Kamineni Institute of Dental Sciences (IN)
Openalex Percentile: Top 62%
Oral microbiology and periodontitis research
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Assessing anti-plaque efficiency of a herbal dentifrice — Sonia Sharma, Debadrita Ghosh, et al. · Bioinformation (2025) | TGRS Research Map | TGRS