Progress in Utilizing Circ RNAs for Initial Breast Cancer Diagnosis and Prediction

Early detection of breast cancer, a prevalent cancer in women, is vital. Circular RNAs (circRNAs), unique non-coding RNAs characterized by closed circles and prevalent in numerous biological fluids, hold promise for research as biomarkers. Studies have shown that circRNAs are involved in the occurrence and development of breast cancer through a variety of mechanisms, including functioning as microRNA sponges, RNA-binding protein conjugations, regulating gene expression and translation templates, and have significant research value. This examination explores the molecular function of circRNAs in the advancement of breast cancer, the progression of clinical trials aimed at early detection and prognosis, and the exploration of their detection techniques and prospective development opportunities.