Sonoelastography in differentiating benign and malignant thyroid nodules: A histopathological correlation

Thyroid nodules are common and distinguishing benign from malignant ones is essential for optimal management. This cross-sectional study of 120 patients assessed Acoustic Radiation Force Impulse (ARFI) imaging in differentiating thyroid nodules, correlating results with histopathology. Malignant nodules showed higher mean ARFI values (3.59 ± 0.7 m/s) than benign ones (1.98 ± 0.31 m/s). With a 2.8 m/s cutoff, ARFI achieved 92.6% sensitivity and 92.9% specificity. Combining ARFI with conventional ultrasound improved diagnostic accuracy, highlighting its potential to reduce unnecessary biopsies.