Eosinophil Extracellular Trap Remnants as Potential Biomarkers for the Diagnosis and Activity Assessment of Otitis Media Associated With Eosinophilic Granulomatosis With Polyangiitis and Eosinophilic Otitis Media
These preliminary findings suggest that EET remnants in the middle ear lavage may be potentially useful as biomarkers for the diagnosis and disease activity of otologic lesions in EGPA and EOM. It seems acceptable to measure the levels of EET remnants using blood samples in patients with EGPA.
Authors
- Naohiro Yoshida (ORCID: https://orcid.org/0000-0002-7867-8490)
- Aya Honma (ORCID: https://orcid.org/0000-0002-4738-4270)
- Akihiro Homma (ORCID: https://orcid.org/0000-0003-1488-0646)
- Masanobu Suzuki (ORCID: https://orcid.org/0000-0001-5559-0317)
- Atsushi Fukuda (ORCID: https://orcid.org/0000-0001-9204-0007)
- Keishi Fujiwara (ORCID: https://orcid.org/0000-0002-4770-3227)
- Kimiko Hoshino (ORCID: https://orcid.org/0000-0001-8582-7936)
- Yoshihiko Esu (ORCID: https://orcid.org/0000-0002-5133-2270)
- Akira Nakazono (ORCID: https://orcid.org/0000-0001-7517-0977)
- Yuji Nakamaru (ORCID: https://orcid.org/0000-0002-9045-4617)
- Shinya Morita (ORCID: https://orcid.org/0000-0002-2429-9751)
- Kento Komatsuda (ORCID: https://orcid.org/0009-0001-8952-1712)
Institutions
- Jichi Medical University (JP)
- Hokkaido University (JP)
- Jichi Medical University Saitama Medical Center (JP)
Publication Details
- Journal
- Otology & Neurotology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1097/mao.0000000000004739
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 0.00