Two Peas in a Pod: Exploring the Rare Co-existence of Genital and Extragenital Lichen Sclerosus Et Atrophicus in Two Patients

Lichen sclerosus is a chronic inflammatory disease that primarily causes vulval and peri-anal lesion in prepubertal, peri-and post-menopausal women. [1]Hallopeau described it as lichen planus et atrophicus in 1887.Now, the term has been changed to 'lichen sclerosus' since not all cases exhibit epithelial atrophy.e pathogenesis is unclear and female-to-male ratio ranges from 6:1 to 10:1. [1]Lesions are mostly found in the anogenital region.Incidence of extragenital lichen sclerosus et atrophicus (LSA) is 15-20%, [2] found mostly over the neck, shoulders, axillae, trunk and thighs.It is characterised by hyperpigmented/hypopigmented asymptomatic/itchy flat, polygonal papules and plaques with sclerosis and atrophy primarily affecting the vulva, perineum and perianal region in females and prepuce in males.