A randomized comparative study on successional versus premixed intrathecal administration of hyperbaric ropivacaine 0.75% and fentanyl in elective urological surgery

The effects of successional versus premixed administration of fentanyl and hyperbaric ropivacaine for urological surgeries is of interest. Hence, a total of 56 patients were randomized into two groups: Group P received a premixed solution and Group S received fentanyl followed by ropivacaine. Results showed that Group S had an earlier onset and longer duration of sensory and motor blocks, with more stable hemodynamics. Side effects were comparable between the two groups. Thus, we show that successional administration provides faster onset, prolonged block duration and better hemodynamic stability with minimal side effects.