Optimization of the HS-GC/MS technique for urine metabolomic profiling
Optimized preparation protocols enable HS GC/MS method to be effectively applied for the analysis of volatile components in urine samples. The modified HS GC/MS method can be scaled up for large-sample analysis to both detect identified metabolites and explore potential new biomarkers associated with IBD and other pathologies.
Authors
- Andrei V. Chaplin (ORCID: https://orcid.org/0000-0003-1377-7153)
- Irina V. Kolesnikova (ORCID: https://orcid.org/0000-0001-6608-6802)
- Olga Yu. Shagaleeva (ORCID: https://orcid.org/0009-0006-5946-483X)
- Artemiy S. Silantiev
- Б. А. Ефимов (ORCID: https://orcid.org/0009-0003-8879-6516)
- Daria A. Kashatnikova
- Natalya B. Zakharzhevskaya (ORCID: https://orcid.org/0000-0003-1045-1895)
- Dmitry A. Kardonsky (ORCID: https://orcid.org/0000-0001-7231-3629)
- Anna Vanyushkina (ORCID: https://orcid.org/0000-0002-2538-689X)
- Victoriia Kazakova
- E A Vorobyeva
- Tatiana N Kalachnuk
Institutions
- Skolkovo Institute of Science and Technology (RU)
- Pirogov Russian National Research Medical University (RU)
- Vavilov Institute of General Genetics (RU)
- Federal Medical-Biological Agency (RU)
Publication Details
- Journal
- Biology Methods and Protocols
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/biomethods/bpaf079
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00