Causality of atrial fibrillation and left atrial traits: Genetic and epigenetic perspectives
LAaEF is bidirectionally causally linked with AF, underscoring its importance in the management of AF. Epigenetic modifications, as evidenced by specific CpG sites, may contribute to atrial remodeling in AF, offering new avenues for research into the AF pathophysiology.
Authors
- Jie Xu (ORCID: https://orcid.org/0000-0002-2039-7055)
- Yingying Liao (ORCID: https://orcid.org/0000-0001-5423-7028)
- Dihui Cai (ORCID: https://orcid.org/0000-0002-8153-3647)
- Ye Shen (ORCID: https://orcid.org/0000-0001-5235-0182)
- Wei Han (ORCID: https://orcid.org/0009-0002-0078-2105)
- Yuheng Jiao
Institutions
- Shanghai East Hospital (CN)
Publication Details
- Journal
- Heart Rhythm O2
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1016/j.hroo.2025.10.018
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Heilongjiang Province
- Shanghai Pudong New Area Health Commission