Confounding Factors in the Diagnosis of Hereditary Spherocytosis and Gallstone Formation in Related Hemolytic Disorders From a Tertiary Care Center in North India

The development of gallstones in hemolytic disorders involves a multifactorial interplay of hemolysis, bilirubin metabolism, and genetic factors. Homozygous Gilbert syndrome significantly increases the susceptibility to gallstones, highlighting the importance of genetic screening in at-risk patients.

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Publication Details

Journal
Cureus
Published
2025-11-05
DOI
https://doi.org/10.7759/cureus.96168
Primary Topic
Erythrocyte Function and Pathophysiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Confounding Factors in the Diagnosis of Hereditary Spherocytosis and Gallstone Formation in Related Hemolytic Disorders From a Tertiary Care Center in North India

Rajesh Kashyap, J. R. P. Gupta, Rizwan Athar
Cureus
Erythrocyte Function and Pathophysiology
article

Confounding Factors in the Diagnosis of Hereditary Spherocytosis and Gallstone Formation in Related Hemolytic Disorders From a Tertiary Care Center in North India

Rajesh Kashyap, J. R. P. Gupta, Rizwan Athar
article en

Abstract

The development of gallstones in hemolytic disorders involves a multifactorial interplay of hemolysis, bilirubin metabolism, and genetic factors. Homozygous Gilbert syndrome significantly increases the susceptibility to gallstones, highlighting the importance of genetic screening in at-risk patients.

CureusVol. 17(11)
Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
Openalex Percentile: Top 59%
Erythrocyte Function and Pathophysiology
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