Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition

The results suggest that BMI contributes to GMV alterations in PCC patients, with both BMI and GMV demonstrating correlations with peripheral immunological markers. These findings indicate that converging mechanisms involving inflammation and structural brain alterations may contribute to obesity and PCC.

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Publication Details

Journal
Brain Behavior & Immunity - Health
Published
2025-11-06
DOI
https://doi.org/10.1016/j.bbih.2025.101137
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition

Ildikò Rita Dunay, Franziska Schick, Alejandra P. Garza, Sharmili Edwin Thanarajah et al.
Brain Behavior & Immunity - Health
Long-Term Effects of COVID-19
article

Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition

Ildikò Rita Dunay, Franziska Schick, Alejandra P. Garza, Sharmili Edwin Thanarajah, Martin A. Walter, Philipp A. Reuken, Nils Opel, Luise Victoria Claaß, Tonia Rocktäschel, Andreas Stallmach, Bianca Besteher, Kathrin Finke, Christian Gaser
article en

Abstract

The results suggest that BMI contributes to GMV alterations in PCC patients, with both BMI and GMV demonstrating correlations with peripheral immunological markers. These findings indicate that converging mechanisms involving inflammation and structural brain alterations may contribute to obesity and PCC.

Brain Behavior & Immunity - HealthVol. 50
Goethe University Frankfurt (DE), Fraunhofer Institute for Translational Medicine and Pharmacology (DE), Max Planck Institute for Metabolism Research (DE), German Centre for Cardiovascular Research (DE), University Hospital Frankfurt (DE), Jena University Hospital (DE), Franklin University (US), Friedrich Schiller University Jena (DE), Ludwig-Maximilians-Universität München (DE), Otto-von-Guericke-Universität Magdeburg (DE)
Openalex Percentile: Top 54%
Long-Term Effects of COVID-19
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Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition — Ildikò Rita Dunay, Franziska Schick, et al. · Brain Behavior & Immunity - Health (2025) | TGRS Research Map | TGRS