Growth differentiation factor 15 alters intestinal barrier and increases permeability: A new molecular target in inflammatory bowel disease
In the present study, we describe a novel mechanism in IBD pathophysiology, linking mitochondrial stress to the disruption of the intestinal barrier and increased intestinal permeability.
Authors
- Raquel Camargo-Camero
- Maria J. Sanchez‐Quintero (ORCID: https://orcid.org/0000-0002-5638-2920)
- Guillermo Alcaín‐Martínez
- Alejandra Fernández-Castañer
- Ada del Mar Carmona-Segovia (ORCID: https://orcid.org/0000-0002-2031-2760)
- Cristina Rodriguez (ORCID: https://orcid.org/0000-0002-2442-2908)
- Juan Antonio López-Villodres (ORCID: https://orcid.org/0000-0002-2451-7245)
- Antonio Jesús Ruiz‐Malagón (ORCID: https://orcid.org/0000-0003-4323-650X)
- Víctor Manuel Becerra‐Muñoz (ORCID: https://orcid.org/0000-0001-6454-7644)
- Isabel Arranz‐Salas (ORCID: https://orcid.org/0000-0003-3603-9516)
- Carlos Lopez‐Gómez (ORCID: https://orcid.org/0000-0003-2699-451X)
- Eduardo Garcı́a-Fuentes (ORCID: https://orcid.org/0000-0002-3491-2724)
- Francisco J. Rodríguez-González (ORCID: https://orcid.org/0000-0002-5136-4854)
- Manuel Jiménez-Navarro
- Marina Herraiz-Vilela
- Fernando Gutiérrez-Martínez
- Raquel Serrano-Pino
- Paula García-Ávila
- Luis Díaz-Suárez
Institutions
- Instituto de Salud Carlos III (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-11-06
- DOI
- https://doi.org/10.3748/wjg.v31.i41.110955
- Citations
- 2
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 3.34