Deep Granuloma Annulare After Scalp Infection: Wolf’s Isotopic Response in a Pediatric Patient

We present a case of a pediatric patient with recurrent flares of deep granuloma annulare (GA) largely localized to the right scalp and face, corresponding to the area of a previously resolved scalp infection. This clinical pattern is suggestive of Wolf's isotopic response, a phenomenon that has been rarely reported in children. To our knowledge, this may represent one of the first documented cases of deep GA manifesting as Wolf's isotopic response in a pediatric patient.

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Publication Details

Journal
Cureus
Published
2025-11-05
DOI
https://doi.org/10.7759/cureus.96166
Primary Topic
Skin Diseases and Diabetes
Type
article
Field-Weighted Citation Impact
0.00
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article

Deep Granuloma Annulare After Scalp Infection: Wolf’s Isotopic Response in a Pediatric Patient

Elaine S. Keung, Luke Bloomquist, Shena Kravitz, Henok Eskinder et al.
Cureus
Skin Diseases and Diabetes
article

Deep Granuloma Annulare After Scalp Infection: Wolf’s Isotopic Response in a Pediatric Patient

Elaine S. Keung, Luke Bloomquist, Shena Kravitz, Henok Eskinder, Juliana M O'Reilly
article en

Abstract

We present a case of a pediatric patient with recurrent flares of deep granuloma annulare (GA) largely localized to the right scalp and face, corresponding to the area of a previously resolved scalp infection. This clinical pattern is suggestive of Wolf's isotopic response, a phenomenon that has been rarely reported in children. To our knowledge, this may represent one of the first documented cases of deep GA manifesting as Wolf's isotopic response in a pediatric patient.

CureusVol. 17(11)
Landstuhl Regional Medical Center (DE), Madigan Army Medical Center (US), Walter Reed National Military Medical Center (US)
Openalex Percentile: Top 46%
Skin Diseases and Diabetes
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