Natural History and Clinical Associations of Plasma Vascular Endothelial Growth Factor A
Severe traumatic brain injury (TBI) is associated with secondary injury and poor outcomes, but the underlying mechanisms are poorly understood. Vascular mechanisms may be important. We aimed to characterize how blood vascular endothelial growth factor A (VEGF-A) levels are affected by TBI, and its associations with secondary injury and functional outcome.
Authors
- Primož Gradišek
- Guido Bertolini (ORCID: https://orcid.org/0000-0002-3101-4259)
- Eleftheria Kodosaki (ORCID: https://orcid.org/0000-0003-1086-6409)
- Deborah Novelli (ORCID: https://orcid.org/0000-0002-2749-304X)
- David Sharp (ORCID: https://orcid.org/0000-0003-4995-2240)
- Eyal Soreq (ORCID: https://orcid.org/0000-0003-4809-4889)
- Elena Garbero (ORCID: https://orcid.org/0000-0003-4902-0144)
- Karl Zimmerman (ORCID: https://orcid.org/0000-0003-1239-3414)
- Sandra Magnoni (ORCID: https://orcid.org/0000-0002-1723-0844)
- Amanda Heslegrave (ORCID: https://orcid.org/0000-0002-7290-6405)
- Giovanni Nattino (ORCID: https://orcid.org/0000-0002-3034-6251)
- Neil M.H. Graham (ORCID: https://orcid.org/0000-0002-1236-2311)
- Henrik Zetterberg (ORCID: https://orcid.org/0000-0003-3930-4354)
- Lucia M. Li (ORCID: https://orcid.org/0000-0001-7339-4854)
- Federico Moro (ORCID: https://orcid.org/0000-0002-2682-5583)
Institutions
- University of Ljubljana (SI)
- University of Sassari (IT)
- Mario Negri Institute for Pharmacological Research (IT)
- UK Dementia Research Institute (GB)
- University College London (GB)
- Imperial College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Neurology Open Access
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1212/wn9.0000000000000039
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00