Brain volumetric reductions in patients with thrombotic thrombocytopenic purpura

Our study demonstrated a significant reduction in brain and nucleus accumbens volume in patients with TTP compared with a healthy control group. These findings suggest a possible lasting impact of TTP on the CNS and highlight the importance of continued monitoring and intervention to reduce neurological complications in patients after the acute phase of the disease. Future studies are needed to validate our results and elucidate the mechanisms underlying the brain changes observed in patients with TTP. Our findings provide valuable information for developing more effective treatment strategies and improving the quality of life of patients with TTP.