Risk of malignant melanoma and colorectal cancer in Birt-Hogg-Dubé syndrome – a matched cohort study
This study confirms the high risk of kidney tumors in BHDS and identifies increased risks for colorectal cancer and malignant melanoma, though the absolute risks remain low. Further research is needed to validate the colorectal cancer association and assess its implications for screening and management.
Authors
- Fulya Taylan (ORCID: https://orcid.org/0000-0002-2907-0235)
- Magnus Nordenskjöld (ORCID: https://orcid.org/0000-0002-4974-425X)
- Anna Skarin Nordenvall (ORCID: https://orcid.org/0000-0003-3034-9222)
- Giorgio Tettamanti
- Maria Soller (ORCID: https://orcid.org/0000-0001-9980-8971)
- Kristina Lagerstedt‐Robinson (ORCID: https://orcid.org/0000-0001-9848-0468)
- Ann Nordgren (ORCID: https://orcid.org/0000-0003-3285-4281)
- Fredrik Persson (ORCID: https://orcid.org/0000-0002-5019-4312)
- Anna Martling (ORCID: https://orcid.org/0000-0001-5998-4735)
Institutions
- Karolinska University Hospital (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1038/s41416-025-03258-0
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancerfonden
- Karolinska Institutet
- Vetenskapsrådet
- Bertil Hållstens Forskningsstiftelse
- Stiftelsen Frimurare Barnhuset i Stockholm