The Impact of Cardiovascular Health in the Association between mind-body Practice and Holistic well-being: Findings from a 20-year Study in US Adults

Abstract Mind-body practice can benefit various physical and mental health conditions. However, the exact role of cardiovascular health in the association between mind-body practice and holistic well-being, as often measured by flourishing, in mid- and late life, remains a growing field of research. This study examined respondents enrolled in waves 1–3 of the Midlife in the United States (MIDUS) study ( N = 2,536; Mage = 65 ± 11, women 55%), merging data from the main self-administered questionnaire and biomarker projects. Holistic well-being was assessed by a composite flourishing score constructed from respondents’ emotional, psychological, and social well-being status. Structural equation models examined whether persistent mind-body practice across two waves (1–2) or intermittent practice at one wave is associated with better flourishing over 20 years, compared to no practice, while controlling for covariates (baseline sociodemographic, health, and functional status). Furthermore, we evaluated whether better cardiovascular health, as assessed by the parameters of Life’s Essential 8 defined by the American Heart Association, mediates the above associations. Only 18% of participants were identified using mind-body practice at any frequency. After controlling for covariates, findings revealed that persistent mind-body practice has a significant positive effect ( b = 1.078; SE = 0.523; p < .05) on flourishing. Although cardiovascular health status has a significant positive effect ( b = 0.325; SE = 0.125; p < .05) on flourishing, it does not mediate the association between persistent mind-body practice and flourishing. More research is necessary, considering other possible confounding factors, to support future policy and practice recommendations aimed at enhancing the overall well-being of middle-aged and older adults.