Extensive ischemic change on stroke presentation is uncommon: A population-based study
In our population, most patients presenting within 24 hours of LKN had ASPECTS ≥6. Even in patients with NIHSS ≥6, only 14 % of patients presenting in the extended time window had ASPECTS <6. These results can inform resource utilization and clinical trial design.
Authors
- Rebecca S. Cornelius
- Mary Haverbusch (ORCID: https://orcid.org/0000-0002-1017-1036)
- Paul S. Horn (ORCID: https://orcid.org/0000-0002-4990-5754)
- Shantala Gangatirkar
- David Robinson (ORCID: https://orcid.org/0000-0003-3221-3599)
- Janice Carrozzella (ORCID: https://orcid.org/0000-0001-6130-4057)
- Thomas Maloney (ORCID: https://orcid.org/0000-0002-2643-9009)
- Eva A. Mistry (ORCID: https://orcid.org/0000-0002-7426-3650)
- Thomas A. Tomsick (ORCID: https://orcid.org/0000-0002-8053-1551)
- Robert J. Stanton (ORCID: https://orcid.org/0000-0003-3804-5063)
- Yasmin Tarek Ali Abdel Aziz (ORCID: https://orcid.org/0000-0002-3515-4005)
- Brady J. Williamson (ORCID: https://orcid.org/0000-0002-1161-402X)
- Heidi Sucharew (ORCID: https://orcid.org/0000-0002-3933-1574)
- Vivek Khandwala (ORCID: https://orcid.org/0000-0002-6076-2395)
- David T. Wang (ORCID: https://orcid.org/0000-0002-2656-8951)
- Pooja Kumari Khatri (ORCID: https://orcid.org/0000-0002-7344-8266)
- Lily Wang (ORCID: https://orcid.org/0000-0002-5107-438X)
- Brett Kissela (ORCID: https://orcid.org/0000-0002-4839-3814)
- Achala Vagal
- Mary Gaskill-Shipley
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Parks Victoria (AU)
- Yale University (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108488
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00