Detection and molecular characterisation of tick-borne encephalitis virus in CSF and serum in relation to disease severity
TBEV RNA was detectable in both serum and CSF of TBE patients, and its presence was associated with more frequent ICU admission and need for mechanical ventilation. Sequencing of the 5'NCR revealed genetic variation between TBEV sequences from patients in Örebro and Värmland.
Authors
- Anita Koskela von Sydow
- Anna Jonsson Henningsson (ORCID: https://orcid.org/0000-0002-9315-8901)
- Martin Sundqvist (ORCID: https://orcid.org/0009-0003-7928-9555)
- Naveed Asghar (ORCID: https://orcid.org/0000-0003-4442-8503)
- Per‐Eric Lindgren (ORCID: https://orcid.org/0000-0003-2767-3638)
- Magnus Johansson (ORCID: https://orcid.org/0000-0003-3962-2141)
- Lukas Frans Ocias (ORCID: https://orcid.org/0000-0003-3437-0897)
- Magnus Klinteskog
Institutions
- Uppsala University Hospital (SE)
- Örebro University (SE)
- Region Jönköpings län (SE)
- Karlstad University (SE)
Publication Details
- Journal
- Journal of Clinical Virology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1016/j.jcv.2025.105885
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Region Värmland