Delivery of GRg3 via alginate/PLGA nanoparticles: physicochemical, cellular, and <i>in vivo</i> biocompatibility assessments
Encapsulation of GRg3 in alginate/PLGA NPs enhanced its stability, anticancer activity, and antioxidant potential without systemic toxicity. These findings highlight the promise of GRg3-loaded nanocarriers for cancer therapy, warranting further evaluation in disease-specific models.
Authors
- Mohammad Reza Hajinezhad (ORCID: https://orcid.org/0000-0002-3825-4714)
- Shekoufeh Mirinejad (ORCID: https://orcid.org/0000-0003-0714-6507)
- Mahmood Barani (ORCID: https://orcid.org/0000-0002-1711-2522)
- Mahdi Majidpour (ORCID: https://orcid.org/0000-0002-3696-6953)
- Fatemeh Madani (ORCID: https://orcid.org/0000-0001-9535-2743)
- Saman Sargazi (ORCID: https://orcid.org/0000-0002-2255-5977)
Institutions
- Zabol University (IR)
- Zahedan University of Medical Sciences (IR)
- Cellular Research (United States) (US)
- Tehran University of Medical Sciences (IR)
- Persian Gulf University (IR)
Publication Details
- Journal
- Drug Development and Industrial Pharmacy
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1080/03639045.2025.2585400
- Primary Topic
- Graphene and Nanomaterials Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00