Multicenter randomized phase II study of R-MPV-A chemoimmunotherapy with or without low-dose whole-brain radiotherapy for newly-diagnosed primary CNS lymphoma
R-MPV-A is a highly efficacious and safe regimen with or without LD-WBRT. LD-WBRT contributes to disease control and increases PFS in PCNSL.
Authors
- Jeffrey Scott Wefel (ORCID: https://orcid.org/0000-0003-3584-023X)
- Lisa Marie DeAngelis (ORCID: https://orcid.org/0000-0002-6290-7818)
- Christian Grommes
- Sanjay Aneja (ORCID: https://orcid.org/0000-0001-5681-7528)
- Antonio M. P. Omuro (ORCID: https://orcid.org/0000-0003-4299-3664)
- Minesh P. Mehta (ORCID: https://orcid.org/0000-0002-4812-5713)
- Eric D. Donnelly (ORCID: https://orcid.org/0000-0001-6028-7128)
- Ya-Yu Tsai (ORCID: https://orcid.org/0000-0002-0621-9519)
- Minhee Won (ORCID: https://orcid.org/0000-0003-2214-282X)
- Denise D. Correa (ORCID: https://orcid.org/0000-0002-7423-8172)
- Mei‐Yin C. Polley (ORCID: https://orcid.org/0000-0003-0106-0323)
- David M. Peereboom (ORCID: https://orcid.org/0000-0001-7798-5176)
- Joseph Bovi (ORCID: https://orcid.org/0000-0002-3686-1940)
- Tim Struve
- Leland Rogers (ORCID: https://orcid.org/0000-0002-5978-8838)
- Benjamin W. Corn (ORCID: https://orcid.org/0000-0002-2881-0326)
- Maria Werner‐Wasik
- Enrico C. Lallana
- FABIO MASSAITI IWAMOTO (ORCID: https://orcid.org/0000-0003-1397-9927)
- Marc Rosenblum
Institutions
- Northwestern University (US)
- Baptist Hospital of Miami (US)
- Cleveland Clinic (US)
- Memorial Sloan Kettering Cancer Center (US)
- NorthShore University HealthSystem (US)
- Kaiser Permanente (US)
- The University of Texas MD Anderson Cancer Center (US)
- Chicago Department of Public Health (US)
- Palo Alto University (US)
- Thomas Jefferson University Hospital (US)
- Kaiser Permanente Oakland Medical Center (US)
- Shaare Zedek Medical Center (IL)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Yale University (US)
- Utah Cancer Specialists (US)
- Office of Minority Health (US)
- ThedaCare (US)
- Regional Cancer Center (US)
- Stanford Medicine (US)
- Miami Transplant Institute (US)
- NRG Oncology (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1093/neuonc/noaf221
- Citations
- 5
- Primary Topic
- CNS Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.95