Influenza A-associated acute necrotizing encephalopathy in an immunocompetent adult

Acute necrotizing encephalopathy (ANE) in the setting of Influenza A infection clinically manifests with high-grade fever and neurological semiology, including diplopia and epileptic episodes as seen in this patient.Core therapeutic management of ANE involves the administration of oseltamivir, intravenous corticosteroids and gamma globulin.The present case report underlines the abrupt clinical deterioration of an immunocompetent patient with Influenza A-induced ANE, over a 3-day onset of flu-like symptoms.