Severe pneumonia with <i>Mycoplasma pneumoniae</i> -induced raѕh and mucositis in an 8-year-old boy

<i>Mycoplasma pneumoniae</i> is a common cause of community-acquired pneumonia (CAP) in children. While <i>M. pneumoniae</i> infection is typically mild and self-limiting, individuals of all ages may develop severe CAP or extrapulmonary manifestations such as <i>M. pneumoniae</i>-induced rash and mucositis (MIRM). Severe <i>M. pneumoniae</i> pneumonia with concurrent MIRM in an 8-year-old boy is reported. The clinical course was complicated by persistent fever, severe mucositis and bilateral multi-lobar pneumonia requiring advanced respiratory support. Initial antibiotic and supportive therapy yielded little improvement, but the introduction of corticosteroids resulted in marked clinical improvement of both the pneumonia and mucositis. This case emphasises that MIRM may indicate a more severe course of <i>M. pneumoniae</i> infection, and that early corticosteroid therapy could be beneficial in such cases.<b>Abbreviations</b>: CAP: community-acquired pneumonia; CRP: C-reactive protein; EM: erythema multiforme; HFNC: high-flow nasal cannula; MIRM: Mycoplasma pneumoniae-induced rash and mucositis; PCR: polymerase chain reaction; RIME: reactive infectious mucocutaneous eruption; SJS: Stevens-Johnson syndrome; TEN: toxic epidermal necrolysis; MIRM: <i>Mycoplasma pneumonia-induced</i>.

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Publication Details

Journal
Paediatrics and International Child Health
Published
2025-10-02
DOI
https://doi.org/10.1080/20469047.2025.2583688
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

Severe pneumonia with Mycoplasma pneumoniae -induced raѕh and mucositis in an 8-year-old boy

Nursel Atay Ünal, Meltem Polat, Anıl Tapısız, Tuğba Bedir Demirdağ
Paediatrics and International Child Health
Pneumonia and Respiratory Infections
article

Severe pneumonia with Mycoplasma pneumoniae -induced raѕh and mucositis in an 8-year-old boy

Nursel Atay Ünal, Meltem Polat, Anıl Tapısız, Tuğba Bedir Demirdağ
article en

Abstract

<i>Mycoplasma pneumoniae</i> is a common cause of community-acquired pneumonia (CAP) in children. While <i>M. pneumoniae</i> infection is typically mild and self-limiting, individuals of all ages may develop severe CAP or extrapulmonary manifestations such as <i>M. pneumoniae</i>-induced rash and mucositis (MIRM). Severe <i>M. pneumoniae</i> pneumonia with concurrent MIRM in an 8-year-old boy is reported. The clinical course was complicated by persistent fever, severe mucositis and bilateral multi-lobar pneumonia requiring advanced respiratory support. Initial antibiotic and supportive therapy yielded little improvement, but the introduction of corticosteroids resulted in marked clinical improvement of both the pneumonia and mucositis. This case emphasises that MIRM may indicate a more severe course of <i>M. pneumoniae</i> infection, and that early corticosteroid therapy could be beneficial in such cases.<b>Abbreviations</b>: CAP: community-acquired pneumonia; CRP: C-reactive protein; EM: erythema multiforme; HFNC: high-flow nasal cannula; MIRM: Mycoplasma pneumoniae-induced rash and mucositis; PCR: polymerase chain reaction; RIME: reactive infectious mucocutaneous eruption; SJS: Stevens-Johnson syndrome; TEN: toxic epidermal necrolysis; MIRM: <i>Mycoplasma pneumonia-induced</i>.

Paediatrics and International Child HealthVol. 45(3-4)
Gazi University (TR)
Openalex Percentile: Top 57%
Pneumonia and Respiratory Infections
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