Associations between structural injury and task-based corticomuscular connectivity after stroke

Findings exclusive to CST injury/integrity subgroups underscore the complexity of structure-function relationships in stroke. Associations between CMC measures in motor-relevant frequency bands with measures reflecting CST microstructure suggest that post-stroke structural injury modulates task-based corticomuscular connectivity. The identification of specific cortical regions and muscles depicts varying adaptive and/or compensatory neuroplastic-like mechanisms, providing mechanistic insights that could inform targeted rehabilitation strategies to optimize post-stroke recovery.